Except for some changes in the naming of the equipment packages - the former top-of-the-line "LS"-model now carries an "LT"-tag, while the "LS" replaces the former "Base" model - the Chevrolet Colorado carries over to the 2006 model-year virtually unchanged. "LT"-models receive upgraded cloth seat-upholstery, and the exterior-color palette is enriched by the addition of Blue Granite. Apart from that, an optional "Sun and Sound Package" equips "LT"-models with a power sunroof and 6-disc in-dash CD-changer.

The 2006 Chevrolet Colorado Mid-Size Pickup Truck compares to the Dodge Dakota, Ford Ranger, GMC Canyon, Nissan Frontier, and Toyota Tacoma.